Why the study?
Does removal of venous endothelium alter vasomotor responses to acetylcholine and glyceryl trinitrate in humans?
Does removal of venous endothelium alter vasomotor responses to acetylcholine and glyceryl trinitrate in humans?
This study provides the first direct evidence for endothelium-dependent dilatation in humans in vivo, suggesting that basal release of EDRF determines resting venous tone.
No takes yet. Share an insight, caveat, or question.
No immediate clinical implications for venous tone; first direct human evidence extends animal data but leaves relevance open.
Collier et al. (1989) studied this question.
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