Why the study?
Is there an association between hepatitis C virus (HCV) infection and hypertrophic cardiomyopathy?
Population
65 patients with hypertrophic cardiomyopathy and a control population of voluntary blood donors in Japan.
Design
Case-control
Authors
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HCV seropositivity was associated with HCM; hypothesis-generating for causality and should not yet change screening or practice.
Is there an association between hepatitis C virus (HCV) infection and hypertrophic cardiomyopathy?
There is a significantly higher prevalence of HCV infection in patients with HCM, particularly the apical variant, suggesting a potential causal role in the pathogenesis of the disease.
Matsumori et al. (1999) studied this question.
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