Key result
HCM is linked to a ~7-fold higher prevalence of HCV antibodies versus volunteer blood donors.
Population
70 patients with hypertrophic cardiomyopathy (mean age 57.7 years) and 1039 volunteer blood donors
Design
Case-control
Authors
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HCV seropositivity may associate with hypertrophic cardiomyopathy; this hypothesis-generating observation leaves open any causal link or screening implications.
Absolute Event Rate: 15.7% vs 2.4%
Patients with hypertrophic cardiomyopathy demonstrated a notably higher prevalence of hepatitis C virus antibodies compared to volunteer blood donors, suggesting a potential association.
Akira Matsumori (1998) conducted a letter in Hypertrophic cardiomyopathy (n=1,109). Hypertrophic cardiomyopathy vs. Volunteer blood donors was evaluated on Hepatitis C virus antibody positivity. Hepatitis C virus antibody was present in 15.7% of patients with hypertrophic cardiomyopathy compared with 2.4% of volunteer blood donors.
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