The high rate of IMP formation during muscle contraction requires a combination of metabolic stress and high ATP turnover, rather than just changes in the intracellular chemical environment.
No takes yet. Share an insight, caveat, or question.
Animal data indicate metabolic stress alone insufficient for high IMP formation; hypothesis-generating for ischemic muscle mechanisms in humans.
Sahlin et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: