March 16, 2018APL BioengineeringOpen Access

Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet

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Structured PICO

Population

2 patient-specific aorta models with an abnormal aortic valve (1 severe aortic valve stenosis, 1 mechanical valve)

Intervention

Computational analysis using 3D phase-contrast magnetic resonance imaging derived velocity profiles as inlet boundary conditions

Comparator

Flat profile and 1D through-plane velocity profiles

Outcome

Flow patterns, peak and mean velocities, helical flow descriptors, and wall shear stress (WSS)-derived indices in the thoracic aortasurrogate

Using 3D velocity profiles as inlet boundary conditions is essential for accurate patient-specific computational analysis of hemodynamics in the ascending aorta and aortic arch in patients with abnormal aortic valves.

Discussion

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Implication

Incorporating secondary inlet flow improves CFD accuracy near abnormal aortic valves; leaves open whether it refines patient-specific risk assessment.

Cite This Study

Pirola et al. (2018) studied this question.

synapsesocial.com/papers/6a6f94aa75498292b708f6d9 https://doi.org/10.1063/1.5011960

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Implication

Incorporating secondary inlet flow improves CFD accuracy near abnormal aortic valves; leaves open whether it refines patient-specific risk assessment.

Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet

Structured PICO

Discussion

Implication

Cite This Study

Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider