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November 1, 1996Journal of Biological ChemistryOpen Access

Slowed Release of Thrombin-cleaved Factor VIII from von Willebrand Factor by a Monoclonal and a Human Antibody Is a Novel Mechanism for Factor VIII Inhibition

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Authors

ESEvgueni L. SaenkoCenter for Theoretical Problems of Physicochemical PharmacologyMSMidori ShimaNara Medical UniversityGGGary E. GilbertVA Boston Healthcare System

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Saenko et al. (1996) studied this question.

synapsesocial.com/papers/6a6f9791e5469ee92be07edehttps://doi.org/10.1074/jbc.271.44.27424
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit1991 · 216 citations
  2. 2A Soluble Recombinant Factor VIII Fragment Containing the A2 Domain Binds to Some Human Anti-Factor VIII Antibodies that Are not Detected by Immunoblotting1992 · 53 citations