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T:EIE research described in this paper, though its actual point of departure had an intention quite different', ultimately resolved itself into an endeavour to throw .light upon the chemical nature and physiological significance of a constituent of living tissues, which, though hitherto of unknown nature, has long carried a name. There can scarcely be a doubt that the substance to be described is the "Philothion" of de Rey-Pailhade.
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Frederick Gowland Hopkins (1921) studied this question.
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