Population
Isolated and cannulated rat skeletal muscle arterioles
Design
Preclinical
Authors
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Hypothesis-generating in rodent arterioles; leaves open translation to human myogenic tone and vascular autoregulation.
In rat skeletal muscle arterioles, depolarization-mediated Ca2+ entry and sarcoplasmic reticulum Ca2+ release interact to maintain myogenic constriction, demonstrating a complex relationship between membrane potential and Ca2+ availability.
Kotecha et al. (2005) studied this question.
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