Population
Rat cremaster muscle arterioles
Comparison
Acute increases in intraluminal pressure and… vs Baseline/control values
Design
Preclinical
Authors
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Animal data distinguish myogenic from agonist-induced arteriolar responses; leaves open translation to human vascular disease.
The study demonstrates that spontaneous arteriolar tone requires increases in intracellular Ca2+ and myosin light-chain phosphorylation, with distinct signaling patterns between myogenic and norepinephrine-induced responses.
Zou et al. (2000) studied this question.
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