Oral sustained drug release and specific site drug delivery system in pharmaceutical field to achieve improved therapeutic advantage. Drug absorption in GIT varies and increased gastric retention time of the dosage form extends the time of drug absorption. It is one of the novel drug delivery system to prolong gastric residence time. Thereby implementing site specific drug release in the stomach for local and systemic effect. It is very useful for the drugs which having narrow absorption Rate. Various forms of gastro retentive drug delivery system, such as floating and non-floating. This article can give an account on merits, demerits and evaluation parameters of gastro retentive system.
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Goud et al. (2016) studied this question.
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