Prospective observational study reveals strong correlation between point-of-care and semiautomated plasma D-dimer testing, indicating portable devices provide reliable thrombosis screening.
Background and Aim: D Dimer is a soluble fibrin degradation product, the estimation of which is used to identify intravascular thrombosis.Different types of D Dimer assays are available commercially which help to diagnose VTE/PE/DIC.The aim of this study was to compare plasma D Dimer values on POCT and Semi-auto analyser over random samples received in the lab and correlate the performance of both.Method: A prospective observational study conducted in a tertiary care hospital in Telangana.Results: Main outcome measures were the statistical correlation of the two methods.The results showed that there was strong correlation of POCT D-Dimer values with Semi-automated method.The correlation between the two was significant with r value of 0.846.When subjected to regression analysis, it was not significant indicating that both values were almost comparable and that POCT was not superior to Semi automated method.Conclusion: The POCT device was comparable with existing Semiautoanalyzer and can be used for reliable estimation of D Dimer.
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Malathi et al. (2021) studied this question.
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