Key result
Latex-enhanced immunoturbidimetry enables reliable D-dimer measurement in serum instead of plasma.
Why the study?
Serum is traditionally considered unsuitable for D-dimer assays due to potential fibrinolytic activity causing falsely increased concentrations, necessitating evaluation of alternative measurement methods.
Can latex-enhanced immunoturbidimetry be used to accurately determine D-dimer concentrations in serum samples?
Comparison
Latex-enhanced immunoturbidimetric measurement in serum vs routine plasma measurement
Design
Other
Authors
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D-dimer reliably signals coagulation activation; leaves open expanded diagnostic roles pending validation studies.
Can latex-enhanced immunoturbidimetry be used to accurately determine D-dimer concentrations in serum samples?
Latex-enhanced immunoturbidimetry enables the use of serum for D-dimer testing, challenging the traditional belief that only plasma is suitable.
Korte et al. (2000) studied D-dimer determination. Latex-enhanced immunoturbidimetry in serum vs. Plasma was evaluated on D-dimer concentration measurement. Latex-enhanced immunoturbidimetric measurement allows the use of serum as a matrix for determining D-dimer concentrations.
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