Key result
Elevated levels of C-reactive protein are associated with only a moderate increase in coronary heart disease risk, adding little predictive value beyond traditional risk factors.
In this issue of the Journal, Danesh and colleagues report that elevated levels of C-reactive protein (CRP) are associated with only a moderate increase in the risk of coronary heart disease (CHD).1 Although these findings are in line with those of other large studies, the independent relative risk associated with increased CRP levels is considerably less than in some earlier reports. Using a multivariate analysis, the authors found that the predictive value of CRP measurement adds relatively little to that provided by assessments of traditional risk factors. In contrast, a smaller study suggested that the CRP level could be more . . .
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Alan R. Tall (2004) conducted an editorial in Coronary heart disease (CHD). Elevated C-reactive protein (CRP) was evaluated on Risk of coronary heart disease (CHD). Elevated levels of C-reactive protein are associated with only a moderate increase in coronary heart disease risk, adding little predictive value beyond traditional risk factors.
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