Why the study?
Does sublingual nitroglycerin improve myocardial blood flow during atrial pacing in patients with three-vessel coronary artery disease?
Population
16 patients, 10 with significant three-vessel coronary artery disease and 6 without coronary disease
Comparison
Right atrial pacing plus 0.4 mg sublingual… vs Rest and right atrial pacing alone
Design
Other
Authors
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May augment flow during pacing in multivessel CAD; hypothesis-generating and should not yet change practice.
Does sublingual nitroglycerin improve myocardial blood flow during atrial pacing in patients with three-vessel coronary artery disease?
Nitroglycerin increases myocardial blood flow during atrial pacing in patients with severe coronary artery disease, likely due to redistribution of blood flow, whereas it decreases flow in patients without coronary disease.
Knoebel et al. (1973) studied this question.
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