September 1, 1998HepatologyOpen Access

TT-virus infection in north american blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis

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Population

180 individuals including North American blood donors, patients with cryptogenic cirrhosis, idiopathic…

Design

Cross-sectional

Authors

MCMichael CharltonMadrigal Pharmaceuticals (United States)PAPhilip N. AdjeiMayo Clinic JPJohn J. PoteruchaUniversity of North Texas

Discussion

Member takes

Implication

Hypothesis-generating for TTV in cryptogenic liver disease; should not yet change donor screening or practice.

Structured PICO

Population

180 individuals including North American blood donors (n=100), patients with cryptogenic cirrhosis (n=33), idiopathic fulminant hepatic failure (n=11), patients with a history of exposure to blood products (n=11), and patients without parenteral risk factors (n=25).

Outcome

Prevalence of TTV infection detected by TTV DNA in serum using PCRsurrogate

TTV infection is present in North American blood donors and is common in patients with liver disease, including cryptogenic cirrhosis and fulminant hepatic failure.

Cite This Study

Charlton et al. (1998) studied this question.

synapsesocial.com/papers/6a6faf765d37378ac1dcbe2d https://doi.org/10.1002/hep.510280335

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TT-virus infection in north american blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

TT-virus infection in north american blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider