July 3, 2016Infection Genetics and EvolutionOpen Access

Full-genome based molecular characterization of encephalitis-associated bovine astroviruses

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Population

Brain tissues of eight RT-PCR and/or ISH positive cattle with encephalitis

Design

Preclinical

Authors

IBIlias BouzalasCentre for Research and Technology Hellas DWDaniel WüthrichUniversity Hospital of Basel SSSenija Selimovic-HamzaUniversity of Bern

Discussion

Member takes

Implication

Astrovirus warrants consideration in unexplained bovine encephalitis; leaves open the need for prospective validation of prevalence and causality.

Structured PICO

Population

Brain tissues of eight RT-PCR and/or ISH positive cattle with encephalitis

Intervention

Full-genome sequencing and phylogenetic comparison

Outcome

Phylogenetic comparison of genomic RNA and encoded proteinssurrogate

BoAstV CH13/NeuroS1 represents a new genotype species within the genus Mammastrovirus that may have acquired factors contributing to neuroinvasion in cattle.

Cite This Study

Bouzalas et al. (2016) studied this question.

synapsesocial.com/papers/6a6fb060febe604dd7088d13 https://doi.org/10.1016/j.meegid.2016.06.052

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Implication

Astrovirus warrants consideration in unexplained bovine encephalitis; leaves open the need for prospective validation of prevalence and causality.

Full-genome based molecular characterization of encephalitis-associated bovine astroviruses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Full-genome based molecular characterization of encephalitis-associated bovine astroviruses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider