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June 1, 1993Journal of VirologyOpen Access

Subgenomic RNA sequence of human astrovirus supports classification of Astroviridae as a new family of RNA viruses

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Population

Human astrovirus serotype 2

Design

Preclinical

Authors

SMStephan S. MonroeBJBaoming JiangSSS E Stine

Discussion

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Overview

Classification as Astroviridae does not alter clinical management of gastroenteritis; leaves open whether genomic distinctions affect human disease patterns.

Structured PICO

P
Population
Human astrovirus serotype 2
I
Intervention
Sequencing of subgenomic RNA
O
Outcome
Subgenomic RNA sequence and deduced protein sequence

The subgenomic RNA sequence of human astrovirus serotype 2 supports its classification into a new family of RNA viruses, Astroviridae.

Cite This Study

Monroe et al. (1993) studied this question.

synapsesocial.com/papers/6a6fb062febe604dd7088d28https://doi.org/10.1128/jvi.67.6.3611-3614.1993
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cloning and characterization of human astrovirus immunoreactive epitopes1993 · 62 citations
  2. 2Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information1981 · 3,640 citations
  3. 3A comprehensive set of sequence analysis programs for the VAX1984 · 14,425 citations
  4. 4Electron microscopic reporting of gastrointestianal viruses in the United Kingdom, 1985–19871991 · 58 citations
  5. 5Temporal synthesis of proteins and RNAs during human astrovirus infection of cultured cells1991 · 113 citations