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November 21, 2013Journal of General Virology

G8P6 rotaviruses isolated from Amerindian children in Mato Grosso do Sul, Brazil, during 2009: close relationship of the G and P genes with those of bovine and bat strains

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Population

68 stool samples from Brazilian Amerindian children with acute gastroenteritis in Mato Grosso do Sul during…

Design

Other

Authors

ALAdriana LuchsOklahoma State Department of HealthMTMaría do Carmo Sampaio Tavares TimenetskyInstituto Adolfo Lutz

Discussion

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Overview

Alerts to potential zoonotic RVA transmission in indigenous communities; extends animal strain linkages but remains hypothesis-generating.

Structured PICO

P
Population
68 stool samples from Brazilian Amerindian children with acute gastroenteritis in Mato Grosso do Sul during 2009
I
Intervention
Sequence analysis of the two outer capsid proteins (VP4 and VP7) and the inner capsid protein (VP6) of the G8P[6] strains
O
Outcome
Genetic relationship between human and animal group A rotavirus (RVA) strains

G8P[6] rotavirus strains isolated from Brazilian Amerindian children show close genetic relationships to bovine and bat strains, suggesting potential zoonotic transmission.

Cite This Study

Luchs et al. (2013) studied this question.

synapsesocial.com/papers/6a6fb0dffebe604dd7088da1https://doi.org/10.1099/vir.0.058099-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single point mutations may affect the serotype reactivity of serotype G11 porcine rotavirus strains: a widening spectrum?1997 · 83 citations
  2. 2First report of human rotavirus G8P[4] gastroenteritis in India: Evidence of ruminants‐to‐human zoonotic transmission2012 · 36 citations
  3. 3Molecular epidemiology of rotaviral infection in South Indian children with acute diarrhea from 1995–1996 to 1998–19992002 · 47 citations
  4. 4Characterization of Serotype G9 Rotavirus Strains Isolated in the United States and India from 1993 to 20012003 · 91 citations
  5. 5Rotavirus Serotype G9 Strains Belonging to VP7 Gene Phylogenetic Sequence Lineage 1 May Be More Suitable for Serotype G9 Vaccine Candidates than Those Belonging to Lineage 2 or 32004 · 62 citations