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October 1, 1997Journal of Tropical PediatricsOpen Access

Further characterization of field strains of rotavirus from Nigeria VP4 genotype P6 most frequently identified among symptomatically infected children

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Population

39 Rotavirus field isolates from symptomatically infected children in Nigeria

Design

Cross-sectional

Authors

MAMohammed I. AdahFederal University of Agriculture

Discussion

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Overview

Genotype surveillance in Nigerian children may inform regional vaccine strategies; leaves open effectiveness of current formulations.

Structured PICO

P
Population
39 Rotavirus field isolates from symptomatically infected children in Nigeria
I
Intervention
Polymerase chain reaction (PCR) characterization of VP4 types
O
Outcome
VP4 genotype prevalence

Genotype P6 is the most frequent rotavirus VP4 genotype among symptomatically infected children in Nigeria, which has implications for vaccine development.

Cite This Study

Mohammed I. Adah (1997) studied this question.

synapsesocial.com/papers/6a6fb0e1febe604dd7088dbdhttps://doi.org/10.1093/tropej/43.5.267
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Conservation of amino acid sequence of VP8 and cleavage region of 84-kDa outer capsid protein among rotaviruses recovered from asymptomatic neonatal infection.1986 · 105 citations
  2. 2Unusual diversity of human rotavirus G and P genotypes in India1996 · 248 citations
  3. 3Serotype of Nigerian rotavirus strains1997 · 31 citations
  4. 4Identification of group A rotavirus gene 4 types by polymerase chain reaction1992 · 1,409 citations
  5. 5Distribution of serotypes of human rotavirus in different populations1992 · 96 citations