Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1993Journal of Clinical MicrobiologyOpen Access

Typing of human rotavirus VP4 by an enzyme immunoassay using monoclonal antibodies

View Full Paper
Ask AI
Bookmark
Share

Population

13 well-characterized cell culture-adapted human rotaviruses, 6 further strains, and 118 rotavirus-positive…

Design

Other

Authors

BCBarbara S. CoulsonThe Royal Melbourne Hospital

Discussion

Loading...

Member takes

Implication

G-type inference aligns with direct P typing in most strains; leaves open broader validation before scaling rotavirus surveillance.

Structured PICO

P
Population
13 well-characterized cell culture-adapted human rotaviruses, 6 further strains, and 118 rotavirus-positive stools
I
Intervention
Enzyme immunoassay using P-type-specific neutralizing monoclonal antibodies (N-MAbs)
O
Outcome
Identification of P types in clinical specimens

The developed P-typing enzyme immunoassay system is economical and amenable to large-scale use in epidemiological studies for human rotavirus.

Cite This Study

Barbara S. Coulson (1993) studied this question.

synapsesocial.com/papers/6a6fb0e1febe604dd7088dc5https://doi.org/10.1128/jcm.31.1.1-8.1993
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative sensitivities of solid-phase immune electron microscopy and enzyme-linked immunosorbent assay for serotyping of human rotavirus strains with neutralizing monoclonal antibodies1988 · 24 citations
  2. 2Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens1990 · 1,581 citations
  3. 3Specific enzyme-linked immunoassay for rotavirus serotypes 1 and 31985 · 128 citations
  4. 4Acute diarrhea and rotavirus infection in newborn babies and children in Yogyakarta, Indonesia, from June 1978 to June 19791981 · 65 citations
  5. 5Simple and specific enzyme immunoassay using monoclonal antibodies for serotyping human rotaviruses1987 · 207 citations