October 24, 2007New England Journal of Medicine
Scarring in the Heart — A Reversible Phenomenon?
Population
Cardiac fibroblasts derived from the endothelium
Design
Editorial
Authors
Discussion
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Member takes
Implication
Cardiac fibrosis may be a reversible phenomenon modulated by transforming growth factor β1 and bone morphogenic protein 7 acting on endothelial-derived fibroblasts.
Structured PICO
P
Population
Cardiac fibroblasts derived from the endothelium
I
Intervention
Transforming growth factor β1 and bone morphogenic protein 7
O
Outcome
Derivation of fibroblasts from the endothelium
Cardiac fibrosis may be a reversible phenomenon modulated by transforming growth factor β1 and bone morphogenic protein 7 acting on endothelial-derived fibroblasts.
Cite This Study
Jeffrey A. Towbin (2007) studied this question.