Why the study?
Does short-term variability (STV) or triangulation predict proarrhythmic potential of drugs in dog left ventricular midmyocardial myocytes?
Does short-term variability (STV) or triangulation predict proarrhythmic potential of drugs in dog left ventricular midmyocardial myocytes?
Short-term variability of action potential duration in dog left ventricular midmyocardial myocytes is a useful preclinical predictor of drug-induced proarrhythmia.
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Supports STV of APD as preclinical marker in canine myocytes; leaves open validation in intact models or humans.
Abi‐Gerges et al. (2009) studied this question.
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