May 1, 1990Journal of Gerontology
Age-Associated Changes in the Components of Atrioventricular Conduction in Apparently Healthy Volunteers
Structured PICO
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Population
185 healthy volunteers aged 20-83 years from the Baltimore Longitudinal Study of Aging with normal rest and exercise ECGs and a resting P-R interval <210 ms, plus a separate group of 7 asymptomatic older men (mean age 71) with first-degree AV block and 25 age-matched men without AV block.
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Outcome
Components of atrioventricular conduction (P-H interval, H-V interval, proximal P-R segment) measured by high-resolution ECGsurrogate
Age-associated prolongation of the P-R interval is localized to the proximal P-R segment, reflecting delay within the atrioventricular junction rather than the His-Purkinje system.
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Discussion
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Implication
Should not yet alter age-adjusted ECG norms; leaves open whether P-H prolongation predicts incident conduction disease.
Cite This Study
Fleg et al. (1990) studied this question.