Why the study?
Does low-dose prednisolone improve left ventricular function and symptoms in acute eosinophilic myocarditis?
Does low-dose prednisolone improve left ventricular function and symptoms in acute eosinophilic myocarditis?
Low-dose corticosteroid therapy may be an effective initial treatment for selected patients with mild acute eosinophilic myocarditis, with early echocardiography being useful for monitoring clinical response.
Low-dose corticosteroids may rapidly improve herbal-associated eosinophilic myocarditis; hypothesis-generating case leaves causality and generalizability open.
BACKGROUND: Eosinophilic myocarditis encompasses a variety of etiologies and the prognosis varies. For patients with a hypersensitive response to medications, high-dose corticosteroids and discontinuation of culprit medications are the main treatments. CASE PRESENTATION: We reported a young man with biopsy-proven eosinophilic myocarditis which was possibly induced by Chinese herbal medicine. His heart failure and left ventricular hypertrophy improved soon after low-dose corticosteroid. CONCLUSION: Low-dose corticosteroid may be effective in selected patients with eosinophilic myocarditis. Early echocardiographic follow-up is mandatory for evaluation of the clinical response.
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Chen et al. (2017) studied this question.
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