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October 1, 1984Cardiovascular Research

Ascending aortic blood velocity and acceleration using Doppler ultrasound in the assessment of left ventricular function

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Why the study?

Can ascending aortic blood velocity and acceleration measured by Doppler ultrasound noninvasively monitor changes in inotropic state and Starling function?

Population

Subjects undergoing assessment of left ventricular function

Comparison

Lower body pressure and dobutamine infusion vs Baseline conditions

Design

Other

Authors

EBE. D BENNETTSt George's HospitalSBS BarclaySt George's HospitalDADavis AlSt George's Hospital

Discussion

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Implication

Doppler aortic velocity may distinguish inotropy from Starling effects; leaves open validation for clinical monitoring.

Structured PICO

Can ascending aortic blood velocity and acceleration measured by Doppler ultrasound noninvasively monitor changes in inotropic state and Starling function?

P
Population
Subjects undergoing assessment of left ventricular function
I
Intervention
Lower body pressure (to increase preload) and dobutamine infusion (5 micrograms/kg/min, to increase inotropic state)
C
Comparator
Baseline conditions
O
Outcome
Changes in mean velocity (MV), maximum acceleration (MA), stroke volume (SV), cardiac output (CO), and left ventricular end-diastolic dimension (EDD)surrogate

Doppler ultrasound measurement of ascending aortic blood velocity and acceleration allows for rapid, noninvasive monitoring of changes in both inotropic state and Starling function.

Cite This Study

BENNETT et al. (1984) studied this question.

synapsesocial.com/papers/6a6fc07ff44fa9f079dd3d58https://doi.org/10.1093/cvr/18.10.632

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of alterations in left ventricular filling, contractility, and systemic vascular resistance on the ascending aortic blood velocity waveform of normal subjects1991 · 143 citations
  2. 2Noninvasive evaluation of left ventricular performance based on peak aortic blood acceleration measured with a continuous-wave Doppler velocity meter.1986 · 164 citations
  3. 3Detection of exercise induced changes in left ventricular performance by Doppler echocardiography.1987 · 22 citations
  4. 4Doppler Echocardiographic Evaluation of Left Ventricular Function1990 · 14 citations
  5. 5Stroke Volume Measured by Pulsed Ultrasound Doppler and M‐Mode Echocardiography1983 · 7 citations