What question did this study set out to answer?

To evaluate the compliance of large arteries in normal subjects compared to hypertensive patients.

November 1, 1979AJP Heart and Circulatory Physiology

An evaluation of large arteries compliance in man

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Why the study?

Is large arteries compliance reduced in sustained hypertensive patients compared to normal subjects?

Population

35 individuals (12 normal subjects and 23 sustained hypertensive patients of the same age)

Comparison

Measurement of large arteries compliance via… vs Normal subjects

Design

Cross-sectional

Authors

ASA C SimonHôpital Broussais MSM. E. SafarHasanuddin University JLJaime LevensonCornell University

Discussion

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Implication

Supports hypertension link to lower arterial compliance; hypothesis-generating for prognostic value and therapeutic targeting.

Key Points

To evaluate the compliance of large arteries in normal subjects compared to hypertensive patients.
Studied 12 normal subjects and 23 hypertensive patients of the same age.
Analyzed diastolic pressure decay using a monoexponential curve.
Calculated arterial compliance using a model for the vascular system.
Arterial compliance in normal subjects was found to be 1.26 +/- 0.04 ml.mmHg-1.m-2.
Significantly lower compliance in hypertensive patients at 0.88 +/- 0.02 ml.mmHg-1.m-2, P<0.001.

Structured PICO

Is large arteries compliance reduced in sustained hypertensive patients compared to normal subjects?

Population

35 individuals (12 normal subjects and 23 sustained hypertensive patients of the same age)

Intervention

Measurement of large arteries compliance via diastolic pressure decay analysis

Comparator

Normal subjects

Outcome

Large arteries compliance (K value)surrogate

Sustained hypertension is associated with significantly reduced large artery compliance compared to normotensive individuals.

Cite This Study

Simon et al. (1979) studied this question.

synapsesocial.com/papers/6a6fc07ff44fa9f079dd3d59 https://doi.org/10.1152/ajpheart.1979.237.5.h550

Topics

Hypertension management

View Full Paper

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An evaluation of large arteries compliance in man

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

An evaluation of large arteries compliance in man

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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