December 1, 1990Hypertension
Effect of age on the efficacy of blood pressure treatment strategies.
Why the study?
Does the proportion of excess cardiovascular events attributable to systolic blood pressure vary with age, and how does this affect the relative efficacy of mass treatment versus case-finding strategies?
Population
Men and women 45 years of age or older in the United States during 1980.
Design
Other
Follow-up
18 years
Authors
Discussion
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Member takes
Implication
May support mass BP lowering in younger adults and case-finding in older; leaves open prospective validation.
Structured PICO
Does the proportion of excess cardiovascular events attributable to systolic blood pressure vary with age, and how does this affect the relative efficacy of mass treatment versus case-finding strategies?
P
Population
Men and women 45 years of age or older in the United States during 1980.
I
Intervention
Mass treatment strategy (shifting blood pressure distribution downward by a small amount) versus high-risk, hypertensive case-finding and treatment approach.
O
Outcome
Population-attributable risk of all-cause mortality, fatal and nonfatal cardiovascular events (stroke, coronary heart disease, angina, congestive heart failure, and peripheral vascular disease), and stroke incidence due to systolic blood pressure.hard clinical
A mass treatment strategy to lower blood pressure has a greater potential impact in younger populations, whereas a high-risk case-finding approach is more effective in older populations.
Cite This Study
Klag et al. (1990) studied this question.