Population
Patients with poliomyelitis (infantile paralysis) and experimentally infected monkeys
Design
Review
Authors
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Early monkey immunity data informs polio immunology concepts; leaves open human immune serum translation without modern trials.
This historical paper discusses the rationale for using immune human serum to treat poliomyelitis based on early experimental evidence of immunity in monkeys.
Simon Flexner (1916) studied this question.
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