Key result
Convalescent serum prevents the development of characteristic poliomyelitis symptoms in monkeys when injected before or mixed with the virus.
Why the study?
Does convalescent serum prevent the development of characteristic symptoms in monkeys inoculated with poliomyelitis virus?
Does convalescent serum prevent the development of characteristic symptoms in monkeys inoculated with poliomyelitis virus?
Convalescent serum can prevent poliomyelitis symptoms in monkeys if given before or with the virus, but has limited effect once the experimental disease is established.
Answers are grounded in this paper and cite their sources.
Suggests prophylactic potential in experimental polio; leaves open translation to human prevention or treatment.
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Edward B. Shaw (1931) conducted a review in Poliomyelitis. Convalescent or other serum was evaluated. Convalescent serum prevents the development of characteristic poliomyelitis symptoms in monkeys when injected before or mixed with the virus.
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