Key result
Human convalescent serum treatment for acute poliomyelitis has not yielded sufficiently consistent results to warrant a definite statement as to its value.
Why the study?
Does serum treatment improve outcomes in patients with acute poliomyelitis?
Population
Patients with acute poliomyelitis
Design
Review
Authors
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Insufficient evidence precludes routine convalescent serum use in acute poliomyelitis; leaves open questions on optimized CNS delivery in controlled trials.
Does serum treatment improve outcomes in patients with acute poliomyelitis?
Serum treatment for acute poliomyelitis lacks consistent evidence of efficacy, partly due to the inability of subarachnoid injections to reach deep inflammatory foci.
Aycock et al. (1923) conducted a review in acute poliomyelitis. human convalescent serum was evaluated. Human convalescent serum treatment for acute poliomyelitis has not yielded sufficiently consistent results to warrant a definite statement as to its value.
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