Key result
Intraspinous administration of concentrated antipoliomyelitic horse serum before the onset of paralysis effectively prevented paralysis in inoculated monkeys.
Why the study?
Does antipoliomyelitic horse serum concentrate prevent paralysis in monkeys inoculated with poliomyelitis?
Does antipoliomyelitic horse serum concentrate prevent paralysis in monkeys inoculated with poliomyelitis?
Concentrated immune horse serum administered intraspinously effectively prevents paralysis in a monkey model of poliomyelitis.
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Caution against clinical use in poliomyelitis; leaves open translation of intraspinous serum efficacy to humans.
Weyer et al. (1931) studied Poliomyelitis. Antipoliomyelitic horse serum concentrate vs. Human convalescent serum was evaluated on Prevention of paralysis. Intraspinous administration of concentrated antipoliomyelitic horse serum before the onset of paralysis effectively prevented paralysis in inoculated monkeys.
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