Key result
Immune horse serum developed from freshly isolated strains protected monkeys against inoculation of poliomyelitis virus.
Why the study?
Does immune horse serum protect against poliomyelitis virus inoculation in animal models?
Population
Animal models of poliomyelitis (young rabbits, guinea-pigs, and monkeys)
Design
Preclinical
Authors
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May warrant further serum development in primates; leaves open translation to human poliomyelitis prevention.
Does immune horse serum protect against poliomyelitis virus inoculation in animal models?
Early preclinical evidence demonstrating that immune horse serum can protect monkeys against poliomyelitis virus.
Edward C. Rosenow (1918) studied Acute poliomyelitis. Immune horse serum was evaluated on Protection against inoculation of virus. Immune horse serum developed from freshly isolated strains protected monkeys against inoculation of poliomyelitis virus.
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