Outbursts of anger as a trigger of acute cardiovascular events: a systematic review and meta-analysis
Why the study?
Do outbursts of anger trigger the onset of acute cardiovascular events?
Population
9 independent case-crossover studies evaluating patients with acute cardiovascular events
Comparison
Outbursts of anger (brief episodes of anger) vs Other times
Design
Meta-analysis
Follow-up
2 hours
Authors
Discussion
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Member takes
Implication
May inform counseling on emotional triggers; leaves open whether interventions reduce events.
Structured PICO
Do outbursts of anger trigger the onset of acute cardiovascular events?
P
Population
9 independent case-crossover studies evaluating patients with acute cardiovascular events (MI/ACS, ischaemic stroke, ruptured intracranial aneurysm, and ventricular arrhythmia)
I
Intervention
Outbursts of anger (brief episodes of anger)
C
Comparator
Other times (control periods in case-crossover design)
O
Outcome
Onset of acute cardiovascular events (MI, ACS, ischaemic and haemorrhagic stroke, and ventricular arrhythmia) in the 2h following outbursts of angerhard clinical
Brief episodes of anger are associated with a transiently higher risk of acute cardiovascular events in the subsequent 2 hours.
Limitations
- Substantial heterogeneity between the studies
Cite This Study
Mostofsky et al. (2014) studied this question.