Why the study?
Does short-term exposure to ambient PM2.5 increase the risk of ECG evidence of myocardial ischemia in postmenopausal women?
Population
55,529 postmenopausal women from the Women's Health Initiative clinical trial, excluding 2,379 women with…
Design
Cohort
Follow-up
6 days (lag0 through lag5)
Authors
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May signal pollution-related ischemia risk in postmenopausal women; hypothesis-generating and should not change practice without prospective confirmation.
Does short-term exposure to ambient PM2.5 increase the risk of ECG evidence of myocardial ischemia in postmenopausal women?
Short-term exposure to PM2.5 is associated with subclinical ST-T abnormalities and decreased T amplitude on ECG, suggesting a pathway for pollution-induced myocardial ischemia and arrhythmogenesis.
Zhang et al. (2009) studied this question.
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