Population
Patients or experimental models with polymicrobial surgical infections
Design
Review
Authors
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May guide anaerobe coverage in polymicrobial surgical infections; leaves open prospective validation of mechanism-targeted strategies.
This review highlights that microbial synergy in surgical infections is primarily driven by anaerobes inhibiting the phagocytosis of aerobes, alongside nutrient provision and environmental alteration.
Rotstein et al. (1985) studied this question.
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