Why the study?
Does intravenous infusion of quinidine prevent ventricular fibrillation in hypothermic dogs?
Does intravenous infusion of quinidine prevent ventricular fibrillation in hypothermic dogs?
Intravenous quinidine effectively prevents ventricular fibrillation in a canine model of severe hypothermia.
In a series of animals with esophageal temperatures reduced to 10°C or lower by core cooling, ventricular fibrillation has been regularly prevented with intravenous infusion of quinidine.
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Sealy et al. (1959) studied this question.
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