Why the study?
Does low-dose aspirin increase the frequency of gastroduodenal mucosal injuries in patients with ischemic heart disease?
Population
131 patients with ischemic heart disease (IHD) not receiving antiulcer treatment in Japan.
Comparison
Low-dose aspirin vs Non-aspirin users
Design
Cross-sectional
Authors
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Low-dose aspirin was associated with higher gastroduodenal mucosal injury in IHD; leaves open whether gastroprotection is warranted pending prospective trials.
Does low-dose aspirin increase the frequency of gastroduodenal mucosal injuries in patients with ischemic heart disease?
Low-dose aspirin use in patients with ischemic heart disease is associated with a significantly high frequency of gastroduodenal mucosal injuries, even in the absence of antiulcer treatment.
Nema et al. (2008) studied this question.
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