Key result
Low-dose enteric-coated aspirin exposure was associated with a higher rate of ulcer lesions (46.4% vs 22.8%) and strongly predicted gastric ulcers (P<0.001) and short-term mortality (P=0.003).
Why the study?
Does low-dose enteric-coated aspirin increase the risk of gastric ulcers and mortality in patients presenting with gastrointestinal hemorrhage?
Population
633 consecutive patients with gastrointestinal hemorrhage admitted to a tertiary referral hospital for…
Comparison
Low-dose enteric-coated aspirin vs Non-aspirin users
Design
Cohort
Authors
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Caution with low-dose enteric-coated aspirin in GI bleed; observational data leaves open causality and practice change.
Observational (n=633)
No
Does low-dose enteric-coated aspirin increase the risk of gastric ulcers and mortality in patients presenting with gastrointestinal hemorrhage?
Absolute Event Rate: 46.4% vs 22.8%
Mousavi et al. (2013) conducted an observational in Gastrointestinal hemorrhage (n=633). Low-dose enteric-coated aspirin vs. Non-aspirin users was evaluated on Ulcer lesions. Low-dose enteric-coated aspirin exposure was associated with a higher rate of ulcer lesions (46.4% vs 22.8%) and strongly predicted gastric ulcers (P<0.001) and short-term mortality (P=0.003).
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