Key result
Severe gastrointestinal bleeding requiring hospitalization developed in 5 male patients treated with low-dose aspirin (81 mg daily), presenting as asymptomatic 'silent ulcers'.
Population
5 male patients, mean age 68 ± 9.6 years, receiving low-dose aspirin for the secondary prevention of…
Design
Case_series
Follow-up
17 days to 2 years
Authors
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Silent GI bleeding risk may warrant caution with low-dose aspirin in elderly men; case reports leave open need for targeted gastroprotection trials.
Case Report (n=5)
No
Even low-dose aspirin (81 mg daily) used for secondary cardiovascular prevention can cause severe, asymptomatic ('silent') gastrointestinal bleeding requiring hospitalization, particularly in elderly patients.
Uchitani et al. (2001) conducted a case report in Gastrointestinal bleeding (n=5). Low-dose aspirin was evaluated on Severe gastrointestinal bleeding requiring hospitalization. Severe gastrointestinal bleeding requiring hospitalization developed in 5 male patients treated with low-dose aspirin (81 mg daily), presenting as asymptomatic 'silent ulcers'.
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