Mortality trend analysis of ischemic heart disease in China between 2010 and 2019: a joinpoint analysis

Xiaoli Fu; Jing Wang; Shuai Jiang; Jian Wu; Zihan Mu; Yanyu Tang; Suxian Wang; Hang Fu; He Ma; Yaojun Zhao

doi:10.1186/s12889-023-15549-3

April 4, 2023BMC Public HealthOpen Access

Mortality trend analysis of ischemic heart disease in China between 2010 and 2019: a joinpoint analysis

View Full Paper

Ask AI

Bookmark

Share

Why the study?

To evaluate the mortality trend of ischemic heart disease in Chinese residents from 2010 to 2019 to provide a basis for establishing targeted interventions.

Structured PICO

P

Population

Chinese residents from 2010 to 2019, data extracted from the China Death Surveillance Dataset covering more than 300 million people (24% of the country's population).

O

Outcome

Mortality rates and age-adjusted death rates (AADRs) of ischemic heart disease (IHD)hard clinical

Ischemic heart disease mortality and age-adjusted death rates in China increased significantly from 2010 to 2019, particularly among rural residents and females aged 75 years and older, highlighting the need for targeted public health interventions.

Limitations

Omission and underreporting in surveillance data (though seriously underreported points were eliminated)

Implication

Rising IHD mortality trends in China warrant monitoring; leaves open whether targeted interventions can reverse increases.

Abstract

Background This study presented the mortality trend of ischemic heart disease (IHD) in Chinese residents from 2010 to 2019 and provided a basis for further establishment of relevant interventions. Methods Data, such as sex, age, urban and rural areas, and death status, were extracted from the China Death Surveillance Dataset from 2010 to 2019, with mortality and age-adjusted death rates (AADRs) as the main indicators. The joinpoint regression model was used to analyze mortality and AADRs trends in IHD. A semi-structured expert interview was conducted to propose targeted intervention measures and countermeasures. Results We observed an overall upward trend in IHD mortality rates and AADRs in China from 2010 to 2019 (average annual percentage change [AAPC] = 5.14%, AAPC AADRs = 1.60%, P < 0.001). Mortality rates and AADRs increased for both males (AAPC = 4.91%, AAPC AADRs = 1.09%, P < 0.05) and females (AAPC = 5.57%, AAPC AADRs = 1.84%, P < 0.001), with higher mortality rate for males than females but higher variation for females than males. Urban (AAPC = 4.80%, AAPC AADRs = 1.76%, P < 0.05) and rural (AAPC = 5.31%, P < 0.001; AAPC AADRs = 0.99%, P > 0.05) mortality rates increased, with the mortality rate higher in rural areas than in urban areas. In the age analysis, mortality rate was higher in middle-aged and older adults than in other age groups. The age-sex cross-analysis found the highest trend in mortality rates among females aged ≥ 75 years (annual percentage change [APC] = 2.43%, P < 0.05). Conclusions The upward trend in IHD mortality in China from 2010 to 2019, especially among female residents aged ≥ 75 years, poses continuing challenges to public health policies and actions.