Current observational data suggesting aspirin counteracts ACE inhibitor benefits are insufficient to change clinical practice.
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Current evidence should not change aspirin or ACE inhibitor prescribing; leaves open a potential interaction pending randomized trials.
Observational studies indicate that aspirin may counteract the beneficial effect of angiotensin-converting enzyme (ACE) inhibitors, but the data are not yet sufficient for making firm recommendations. We review the available data and offer tentative conclusions.
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Peterson et al. (2001) studied this question.
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