Why the study?
Do regional blood volume redistribution and peripheral blood flow patterns during upright tilt differ among variants of postural tachycardia syndrome compared to healthy controls?
Population
37 patients with postural tachycardia syndrome aged 14-21 years and 12 healthy control subjects.
Comparison
Assessment of peripheral blood flow and regional… vs Healthy control subjects.
Design
Case-control
Authors
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Supports distinct POTS mechanisms; hypothesis-generating and should not yet change practice.
Do regional blood volume redistribution and peripheral blood flow patterns during upright tilt differ among variants of postural tachycardia syndrome compared to healthy controls?
POTS variants exhibit distinct patterns of regional blood volume redistribution during orthostasis, supporting the hypothesis of different pathophysiologic mechanisms leading to thoracic hypovolemia.
Stewart et al. (2004) studied this question.
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