What question did this study set out to answer?

To examine trends in adult invasive group B streptococcal (GBS) disease between 1990 and 2007 and characterize its epidemiology to inform adult prevention strategies.

May 29, 2009Clinical Infectious DiseasesOpen Access

Increasing Burden of Invasive Group B Streptococcal Disease in Nonpregnant Adults, 1990–2007

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Authors

TSTami H. SkoffCenters for Disease Control and Prevention MFMonica M. FarleyUniversity of North Carolina at Chapel Hill SPSusan PetitConnecticut Department of Public Health

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Implication

Population-based surveillance reveals doubling incidence of invasive group B streptococcal disease in nonpregnant adults, highlighting the growing need for targeted prevention strategies.

Key Points

To examine trends in adult invasive group B streptococcal (GBS) disease between 1990 and 2007 and characterize its epidemiology to inform adult prevention strategies.
Conducted Active Bacterial Core surveillance across selected counties in 10 US states, tracking nonpregnant residents aged ≥18 years with sterile-site GBS isolates (N=19,512).
Calculated incidence using US Census data, abstracted clinical details from medical records, and performed serotyping and antimicrobial susceptibility testing on a patient subset.
Incidence of adult invasive GBS disease doubled from 3.6 per 100,000 persons in 1990 to 7.3 per 100,000 in 2007 (P < .001), with a median patient age of 63 years.
The mean difference in incidence between black and white persons was 4.6 cases per 100,000, and 88.0% of adult patients had ≥1 underlying condition (diabetes in 44.4%).
Primary clinical syndromes in 2007 were bacteremia without focus (39.3%), skin/soft-tissue infection (25.6%), and pneumonia (12.6%), with serotypes V, Ia, II, and III causing 78.5%–80.8% of infections.

Cite This Study

Skoff et al. (2009) studied this question.

synapsesocial.com/papers/6a6fe23a26a7f98052dc7474 https://doi.org/10.1086/599369

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Implication

Population-based surveillance reveals doubling incidence of invasive group B streptococcal disease in nonpregnant adults, highlighting the growing need for targeted prevention strategies.

Increasing Burden of Invasive Group B Streptococcal Disease in Nonpregnant Adults, 1990–2007

Discussion

Member takes

Implication

Key Points

Cite This Study

Increasing Burden of Invasive Group B Streptococcal Disease in Nonpregnant Adults, 1990–2007

Discussion

Member takes

Implication

Key Points

Cite This Study

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