Why the study?
Does enoxaparin clearance predict the risk of haemorrhage in patients with UA and NSTEMI?
Population
448 patients with unstable angina (UA) and non-ST-segment elevation myocardial infarction (NSTEMI)
Design
Cohort
Authors
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Enoxaparin clearance may flag bleeding risk in UA/NSTEMI; hypothesis-generating and requires prospective validation before guiding practice.
Does enoxaparin clearance predict the risk of haemorrhage in patients with UA and NSTEMI?
Enoxaparin clearance is dependent on body weight and renal function, with decreased renal function significantly increasing the risk of haemorrhagic episodes in patients with UA and NSTEMI.
Bruno et al. (2003) studied this question.
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