January 1, 1998Mineral and Electrolyte Metabolism

Physiologic Actions and Molecular Expression of the Renin-Angiotensin System in the Diabetic Rat

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Population

Diabetic rat models and patients with diabetic nephropathy (narrative review)

Design

Review

Authors

SASharon AndersonNorthwestern University

Discussion

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Implication

May support RAS inhibitor refinement in diabetic nephropathy; leaves open whether intrarenal-targeted strategies improve outcomes.

Structured PICO

Population

Diabetic rat models and patients with diabetic nephropathy (narrative review)

Intervention

Pharmacologic interruption of the renin-angiotensin system (ACE inhibitors, Angiotensin II receptor antagonists)

Outcome

Pathogenesis and progression of diabetic nephropathy

This review highlights the critical role of the intrarenal renin-angiotensin system in the progression of diabetic nephropathy, supporting the use of RAS inhibitors.

Cite This Study

Sharon Anderson (1998) studied this question.

synapsesocial.com/papers/6a6ff2ad660549caf2c47ec3 https://doi.org/10.1159/000057402

View Full Paper

Ask AI

Bookmark

Physiologic Actions and Molecular Expression of the Renin-Angiotensin System in the Diabetic Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Physiologic Actions and Molecular Expression of the Renin-Angiotensin System in the Diabetic Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider