Key result
Chest compression rate peaks at ~125/min for ROSC, but shows no discharge survival benefit.
Why the study?
Few studies have reported chest compression rates used during out-of-hospital cardiopulmonary resuscitation or the relationship between rate and outcome.
Does chest compression rate affect return of spontaneous circulation and survival to hospital discharge in patients with out-of-hospital cardiac arrest?
Population
3,098 patients aged ≥ 20 years with out-of-hospital cardiac arrest
Comparison
Different chest compression rates during CPR
Design
Observational study using monitor-defibrillator recordings
Follow-up
Until hospital discharge
Authors
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Supports ~125/min rate hypothesis for ROSC in OHCA; leaves open survival benefit and needs randomized confirmation.
Observational (n=3,098)
Yes
Does chest compression rate affect return of spontaneous circulation and survival to hospital discharge in patients with out-of-hospital cardiac arrest?
p-value: p=0.012
In out-of-hospital cardiac arrest, chest compression rates around 125/min optimize the return of spontaneous circulation, though this does not translate to a significant improvement in survival to hospital discharge.
Idris et al. (2012) conducted an observational in out-of-hospital cardiac arrest (n=3,098). Chest compression rate was evaluated on return of spontaneous circulation (p=0.012). Chest compression rate had a curvilinear association with return of spontaneous circulation, peaking at ≈125/min (P=0.012), but was not associated with survival to hospital discharge.
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