Population
Myocardial tissue explants from patients with ischemic cardiomyopathy (ICM) and control (CNT) subjects
Design
Case-control
Authors
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Should not yet change ICM management; hypothesis-generating for transcriptional targets in ischemic cardiomyopathy.
Downregulation of transcriptional regulators SP100, CITED2, CEBPD, and BCL3 in ischemic cardiomyopathy alters gene networks involved in apoptosis, metabolism, and hypoxic response.
Herrer et al. (2015) studied this question.
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