Why the study?
Is low or "normal" blood pressure associated with an increased risk of mortality in patients with end-stage renal disease on dialysis?
Population
Patients with end-stage renal disease (ESRD) on dialysis therapy
Comparison
Low or "normal" blood pressure vs High blood pressure / general population
Design
Review
Authors
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Low BP targets may not apply in dialysis; leaves open confounding by heart failure in observational data.
Is low or "normal" blood pressure associated with an increased risk of mortality in patients with end-stage renal disease on dialysis?
In ESRD patients on dialysis, low or "normal" blood pressure is paradoxically associated with higher mortality risk, suggesting that standard blood pressure targets may not apply and require careful assessment of cardiac function and fluid balance.
Lacson et al. (2007) studied this question.
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