What question did this study set out to answer?

To estimate the association between prehypertension and the clustering of modifiable cardiovascular disease risk factors.

May 1, 2009Journal of Cardiovascular Pharmacology

Association Between Prehypertension and Clustering of Cardiovascular Disease Risk Factors Among Chinese Adults

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Why the study?

Is prehypertension associated with an increased clustering of cardiovascular disease risk factors in Chinese adults?

Population

15,540 Chinese adults aged 35-74 years from a nationally representative sample surveyed during 2000-2001.

Comparison

Prehypertension and high normal blood pressure vs Optimal blood pressure and normal blood pressure

Design

Cross-sectional

Authors

DYDahai YuKeele University JHJianfeng HuangPreventive Cardiology DHDongsheng HuPreventive Cardiology

Discussion

Member takes

Implication

Prehypertension was associated with greater CVD risk factor clustering in Chinese adults; extends prior observations but leaves causal effects and interventions open.

Key Points

To estimate the association between prehypertension and the clustering of modifiable cardiovascular disease risk factors.
Conducted a nationally representative cross-sectional survey of 15,540 adults aged 35–74 years in China during 2000–2001.
Assessed prehypertension (blood pressure 120–139/80–89 mm Hg) and four modifiable cardiovascular risk factors: dyslipidemia, impaired fasting glucose/diabetes, cigarette smoking, and overweight/obesity using multivariate models.
Among adults with prehypertension, 79.4%, 40.0%, and 11.0% presented with ≥1, ≥2, and ≥3 modifiable cardiovascular disease risk factors, respectively.
Prehypertension was significantly associated with higher odds of having ≥1 (adjusted OR 1.41, 95% CI: 1.24–1.61), ≥2 (adjusted OR 1.45, 95% CI: 1.30–1.61), and ≥3 (adjusted OR 1.96, 95% CI: 1.67–2.29) risk factors compared to optimal blood pressure, accounting for population attributable risk percents of 16.7%, 18.0%, and 31.9%.
Participants with high normal blood pressure (130–139/85–89 mm Hg) showed a higher prevalence, adjusted odds ratios, and population attributable risk of risk factor clustering than those with normal blood pressure (120–129/80–84 mm Hg).

Structured PICO

Is prehypertension associated with an increased clustering of cardiovascular disease risk factors in Chinese adults?

Population

15,540 Chinese adults aged 35-74 years from a nationally representative sample surveyed during 2000-2001.

Intervention

Prehypertension (120-139/80-89 mm Hg) and high normal blood pressure (130-139/85-89 mm Hg)

Comparator

Optimal blood pressure and normal blood pressure (120-129/80-84 mm Hg)

Outcome

Clustering of ≥1, ≥2, and ≥3 modifiable CVD risk factors (dyslipidemia, impaired fasting glucose/diabetes, cigarette smoking, and overweight/obesity)surrogate

Prehypertension is significantly associated with a clustering of modifiable cardiovascular risk factors among Chinese adults, highlighting the importance of early lifestyle modifications.

Cite This Study

Yu et al. (2009) studied this question.

synapsesocial.com/papers/6a6ffce0660549caf2c48a25 https://doi.org/10.1097/fjc.0b013e3181a02238

Topics

Hypertension management Women and heart disease Lipid management

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Implication

Prehypertension was associated with greater CVD risk factor clustering in Chinese adults; extends prior observations but leaves causal effects and interventions open.

Association Between Prehypertension and Clustering of Cardiovascular Disease Risk Factors Among Chinese Adults

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Association Between Prehypertension and Clustering of Cardiovascular Disease Risk Factors Among Chinese Adults

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider