Why the study?
Do impeller-type centrifugal pumps reduce hemolysis compared to cone-type centrifugal pumps in simulated CPB, ECMO, PCPS, and LVAD conditions?
Population
Experimental conditions simulating cardiopulmonary bypass, extracorporeal membrane oxygenation, percutaneous…
Comparison
Impeller-type centrifugal pumps vs Cone-type centrifugal pump
Design
Preclinical
Authors
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Impeller-type pumps may reduce hemolysis versus cone-type in animal CPB/ECMO/PCPS models; leaves open human translation and practice change.
Do impeller-type centrifugal pumps reduce hemolysis compared to cone-type centrifugal pumps in simulated CPB, ECMO, PCPS, and LVAD conditions?
Impeller-type centrifugal pumps cause less hemolysis than cone-type pumps under high flow/high pressure and low flow/high pressure conditions, suggesting better hemocompatibility for CPB, ECMO, and PCPS.
Kawahito et al. (1997) studied this question.